North York, Ontario
Scientist – 5cP Manufacturing Assistance
Manager 5cP Manufacturing Assistance
12 months contract, extensions after
HOURS OF WORK: Monday to Friday: 8:00 – 4:00 p.m.
REPORTS TO: Head of MA and SPP
Location: Sanofi Pasteur Limited, Toronto, Ontario, Canada
Scientist 5cP Manufacturing Technology is the industrial process know-how SME of the 5cP process/product or area of activity. Scientist 5cP Mtech major role encompasses:
Supports licensed products through the scientific and technical continuous improvement of the existing manufacturing process and support production on a daily basis to reach industrial excellence.
Drives or supports problem-solving by interfacing with Bulk Manufacturing teams, Mtech, Quality, R&D and other functions if needed,
Contributes to strategy related to specific project, process validation, and inspection and audit readiness.
Centralizes all the demands as unique entry point within MTech for Work Request (WR), Not planned short term activity (investigation) and Recurrent activity (at the shop floor) and drives or support the implementations of actions plans.
Support the manufacturing activities, with process and operations-based expertise to support delivery of robust processes with the correct technical solutions, documentation, trained resources, and operating procedures that will ensure consistent manufacturing.
Responsible for ensuring product related technical issue resolution. Apply effective and structured troubleshooting/root cause analysis techniques for production problems as required, and potential improvements in quality and/or yield
Sound knowledge of bacterial upstream and downstream unit operations, which includes high scale fermentation process, micro-filtration, chromatography, fractionation, precipitation, centrifugation, detoxification, ultrafiltration, SIP and CIP.
Responsible for identification of product/process improvements and improvement implementation. Remain up-to-date with new product/process, and process assessment technologies. Determine how such technologies may be applied to increase process efficiency.
Lead or participate on Project Teams, as Manufacturing Technology representative.
Ensure timely completion of all team goals.
Responsible for developing a strong scientific network (internally and externally).
Assist in supervising and training process support staff in managing continuous performance improvement.
Minimum PhD in Biochemist, Chemical Engineering or related fields with 5 years of industrial experience or M.Sc with 10 years of industrial experience. 5+ years demonstrated leadership in behavioral competencies and management. The position also requires additional specific competencies: impact and influence, interpersonal communication, use of technical/professional expertise, resilience and balanced judgement/risk analysis.
Depth knowledge of technical areas specific to upstream (fermentation) and downstream manufacturing processes is required. Sound knowledge in chromatography and protein purification. Expertise in process industrialization will be an asset.
Demonstrated good understanding of current Good Manufacturing Practices, Health and Safety, high quality standards, industry standards and their application to the manufacturing process. Practical experience and knowledge in a GMP, industrial manufacturing environment.
Equipment and process validation experience.
Effective in troubleshooting and root cause analysis.
Strong leadership and project management skills.
Excellent verbal and written communication skills.
Thank you in advance for your interest.
ALTEN PROEX is a Canadian Engineering and Technology Consulting Services company, and a subsidiary of ALTEN Group. Within 30 years, ALTEN has become leader in R&D, Engineering, Information Technology Services, Life Sciences and Network Services with 37,000 consultants working in more than 20 countries.Postule pour ce poste